Mac and the team infiltrate a glamorous hotel used as an international hideout for criminals in order to find a woman with vital information on Codex. However, their target has a new secret identity that includes a completely new face, on the fifth season premiere of MACGYVER, Friday, Dec. 4. Screencaps courtesy of Tatiana

When Taylor’s former protégé is killed while preventing a bio-weapon from falling into the wrong hands, Mac and the team must find the weapon so Desi can pull off the ultimate heist before it’s sold to a terrorist cell, on MACGYVER, Friday, Dec. 11, 2020. Screencaps courtesy of Tatiana and Mianne

When Russ is kidnapped, Mac and the team must break out a previously murderous psychopath, now pacifist, from prison to help find him; while on the run, Mac and Desi are forced to confront their relationship issues. Air date: December 18, 2020

Mac's meeting with Desi's parents goes sideways when her brother finds himself in trouble and desperately needs their help; Russ and Matty must ask an old nemesis for assistance when their new recruitment candidate is kidnapped.

The next episode titled 'Jack + Kinematics + Safe Cracker + MgKNO3 + GTO' will premiere on Friday, January 15, 2021. This will be the second episode of the new year. Although after the fact that episode 4 was full of action, we're expecting to see a bit more on the villain Mason, and the Mac-Desi relationship. Since we know that Riley is also in love with Mac, how she would react to the fact that Mac and Desi seem to be taking their relationship forward. The series also will most likely give us more on Codex as well, since there is the center plot most of the time, even as the Team Pheonix continues with other cases.

During COVID-19's first stay-at-home order, Mac, Bozer and Riley must stop a crime in progress at their neighbor's house; Russ' romantic fling takes on a longer and more complicated turn when they quarantine together.

“Golden Lancehead + Venom + Pole Vault + Blood + Baggage” – The secret experimental cancer treatment Mac’s developing with a friend is discovered when culprits ransack their lab, kidnap Mac’s partner and plan to use the research to create a powerful new nerve agent

“SOS + Hazmat + Ultrasound + Frequency + Malihini” – Mac and team rush to help when Matty’s former mentor, Ian Cain (Robert Patrick), and his embassy staff come down with a deadly, mysterious illness. Also, Taylor and Bozer work with Jerry Ortega (“Hawaii Five-0’s” Jorge Garcia) to infiltrate a Codex cell, on MACGYVER, Friday, Feb.12 (8:00-9:00 PM, ET/PT) on the CBS Television Network.

When Mac and the team are unable to prevent Department of Defense intel from falling into Codex’s hands, Mac must scale a vertical cliff using only gear he can cobble together himself to prevent the info’s transmission, on MACGYVER, Friday, Feb. 19 (8:00-9:00 PM, ET/PT) on the CBS Television Network.

While on a mission to hunt down a Codex lead, Mac and the team discover Murdoc (David Dastmalchian) hacked their comms and has recorded them for months. Now, Mac and the team must stop Murdoc, who is working with Andrews (Joe Pantoliano), as they plot to kill thousands and reveal each Phoenix member’s most-guarded secrets, on MACGYVER, Friday, March 5 (8:00-9:00 PM, ET/PT) on the CBS Television Network.

“C8H7CIO + Nano-Trackers + Resistance + Maldives + Mind Games” – Mac and Riley head overseas together to prevent a governmental collapse and inadvertently inhale new deadly microscopic technology, on MACGYVER, Friday, March 12 (8:00-9:00 PM, ET/PT) on the CBS Television Network.

“Royalty + Marriage + Vivaah Sanskar + Zinc + Henna” – Mac, Desi and Russ go undercover during a royal Indian wedding to protect a princess whose policies could put her life in danger. Also, Russ and Sophia come face-to-face at the wedding, Bozer suspects Riley is up to her old hacking ways and Matty runs down a lead in hopes of getting to the bottom of Mac and Riley’s ingested nano-trackers, on MACGYVER, Friday, April 2 (8:00-9:00 PM, ET/PT) on the CBS Television Network.

“Barn Find + Oil Slick + La Punzonatura + Lab Rats + Tachometer” – While Mac and the team delve into the world of Italian car culture in order to track down a crime boss-in-hiding, Mac must lean on Desi when he discovers that he losing the ability to control his hands. Also, Mac and Desi move in together and Riley reveals the truth about her secret team of hackers to Russ, on MACGYVER, Friday, April 9 (8:00-9:00 PM, ET/PT) on the CBS Television Network.

“H20 + Orthophosphates + Mission City + Corrosion + Origins” – Mac and Desi travel with Bozer to his childhood home when his aunt dies in a tragic accident, however, they soon discover she may have been murdered for trying to expose the city’s contaminated water supply. Also, Riley, Matty and Russ continue to follow leads on their nano-trackers investigation, on MACGYVER, Friday, April 16 (8:00-9:00 PM, ET/PT) on the CBS Television Network. Ernie Hudson and Wendy Raquel Robinson guest star as Bozer’s parents.

“Abduction + Memory + Time + Fireworks + Dispersal” - When Mac and Riley go missing and wake up 24 hours later in a corn field with no memory of how they got there, they must unravel the mystery to find who took them, and how to get rid of the nanotrackers in their bodies, no matter the cost, on the series finale of MACGYVER, Friday, April 30 (8:00-9:00 PM, ET/PT) on the CBS Television Network.