Ex-MI6 agent Russ Taylor recruits former Phoenix Foundation members Mac, Riley, Bozer, Matty and Desi to hunt down a bioweapon that's planned to be used by a mysterious organization for a devastating attack on a major US city.

Gen. John Acosta recruits MacGyver to steal a highly classified project from a military lab to find flaws in its security.

MacGyver and the team are on a plane that's in the air when the pilot has a heart attack.

As MacGyver works quickly to rescue survivors from a collapsed building in Germany, he discovers a new safety threat -- an undetonated bomb from World War II is hidden beneath the rubble.

In an attempt to find the main players in the Codex and cut off their match-fixing funding, Desi goes undercover to infiltrate a soccer team and find the corrupt player working with the shadow organization.

When Russ’ first love, Emilia, is kidnapped by the same rebels he fought during his private military contract days, he takes the Phoenix team to a small, impoverished town to rescue her and rid the town of the rebels for good.

A double date descends into chaos when Mac and Desi witness a murder in the back of the restaurant; as they work to find the killer, Riley tries to keep the secret about her and her friends' "day jobs' from her new boyfriend.

After Oversight is almost killed in a bombing, he recruits Mac to help him find the suspected bomber; Mac meets his Aunt Gwendolyn.

Los Angeles' power grid is taken hostage in a ransomware attack resulting in a citywide blackout; the team discovers the ransomware code used was written by Riley years ago.

When Mac is put into a dream state to help him recall key evidence found in Nikola Tesla's secret lab that could stop Codex's deadly plot, he encounters Nikola Tesla, Alexander Graham Bell, Thomas Edison and his mother.

Mac is placed inside a fake prison cell with a top Codex operative, "The Merchant," to gain his trust and get intel on their next move.

The team is forever altered when MacGyver's Aunt Gwen gets into his head and convinces Mac and Riley to join Codex; Matty and Russ take their concerns about Codex to the White House.

Mac and Riley's mission is interrupted when Russ, Desi and the Phoenix team move to prevent Codex from detonating a weapon of mass destruction; the team discovers Russ' real reason for purchasing the Phoenix Foundation.